Hypoallergenic properties of donkey's milk: a preliminary study

Silvia Vincenzetti, Laura Foghini, Stefania Pucciarelli, Valeria Polzonetti, Natalina Cammertoni, Daniela Beghelli & Paolo Polidori

doi: 10.12834/VetIt.219.125.5
 
 

Summary

Cow's milk protein allergy (CMPA) is an abnormal immunological response to cow milk proteins, which results in IgE-mediated reactions. The therapeutic strategy to respond to CMPA envisages the total elimination of milk or the administration of cow's milk substitutes. For this reason the use of milk from other mammalian species was tested. Among them, donkey's milk proved to be the best alternative in feeding infants affected by CMPA, since its chemical composition is comparable to human milk. In this work an in vitro study was performed in order to analyze the IgE reactivity to milk protein allergens from cow, donkey and goat. In particular, immunoblotting experiments using sera from milk-allergic and non-allergic adult volunteers were conducted with the aim of verifying the hypoallergenic property of donkey's milk. This study provided a preliminary evidence of the hypoallergenicity of donkey's milk when compared to bovine and goat milk. Considering the obtained results, it would be possible to develop a sensitive diagnostic method for CMPA detection, based on chromatographic and immunoblotting analysis.

 
 

Keywords

Cationic exchange chromatography, CMPA, Cow's milk, Donkey's milk, Goat's milk, Immunoblotting, Hypoallergenicity, Reversed-phase chromatography.
 
 
 
© IZSAM Agosto 2016
 
 
 
 
Notizie sull'argomento

Visita studio dalla Georgia

Ketevan Sidamonidze e David Tsereteli del “Richard Lugar Center for Public Health Research” di Tbilisi si sono formati in Istituto sui fattori di rischio, le vie di trasmissione, le azioni di prevenzione e controllo della Brucellosi: una importante zoonosi presente in tutto il mondo.

 

Il cammino del Sistema Sanitario Nazionale verso la One Health

Questo il tema dell’incontro di Roma con la partecipazione del Ministro Schillaci, del Governatore dell’Abruzzo Marco Marsilio, del DG del Ministero Ugo Della Marta, del DG dell’Istituto Nicola D’Alterio, dell’On. Guerino Testa e del Sottosegretario Marcello Gemmato.

 

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