ONE HEALTH
Sanità
 

Animal Health

 

Human, animal and environmental health is part of a single interconnected balance. Animal health is viewed from a broad perspective, understanding the implications it has on public health and food safety.

 
Sanità
 
 
 

Health must be understood as the wellbeing of humans, animals and the environment, each influencing the others in complex and profound ways. The One Health approach, adopted by the Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise, recognises this interdependence and seeks to integrate knowledge and action across all these domains.

 

The Institute’s long-standing focus on animal health is framed within a broader perspective, acknowledging its implications for public health and food safety. Research, prevention and disease surveillance activities are all part of this context, aiming to protect health in all its forms.

In particular, diseases that can be transmitted from animals to humans represent an increasing challenge, further intensified by global dynamics and climate change. At the same time, food safety and ecosystem protection are essential components in ensuring the wellbeing of all. For this reason, the Institute works closely with health authorities and the scientific community to address emerging health challenges in a timely and effective manner.

 

An integrated approach to health, together with scientific research and technological innovation, are vital tools in meeting current and future needs. One Health is not merely a principle, but a practical guide for addressing the complexity of health in an increasingly interconnected world.

 
+ - Projects and Collaborations

Highlighted

Ricerca

Questionario sulla proprietà responsabile del cavallo

Indagine sulla proprietà responsabile del cavallo, con particolare riguardo agli aspetti di biosicurezza in scuderie, maneggi, ippodromi e allevamenti equini.


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+ - Departments

Virology, Cell Cultures and Viral Antigen Development

The Unit is responsible for molecular and serological diagnostics, as well as for the genomic, in vitro and in vivo characterisation of pathogens causing viral infections in domestic and wild animals. It is actively engaged in the surveillance of emerging and re-emerging viral infections, particularly those with zoonotic potential, and in the development and validation of new diagnostic methodologies. Its work is aimed at continuously strengthening diagnostic and biological characterisation capacities for emerging viruses, contributing to the timely and effective management of health emergencies and to the reinforcement of strategies for the prevention and control of infectious diseases.

     

     

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Project Centre

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Mycotoxins, Plant Toxins and Marine Biotoxins

The unit is responsible for the analytical determination of mycotoxins and plant toxins in food intended for human consumption and animal feed, as well as marine biotoxins and other toxins in fishery products. In response to the growing concern over environmental contamination by microplastics, the unit has established a dedicated analytical section focused on the characterisation of these substances in food products, using advanced instrumental analysis techniques.

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Statistical Sciences and GIS

The Department of Statistical Sciences and GIS applies advanced analytics, machine learning, and geographic information systems (GIS) to study the spread of animal diseases. By integrating genomic, epidemiological, and satellite data, it develops predictive models to identify at-risk areas and support containment strategies. Through a One Health approach, it transforms complex data into operational tools for zoonosis prevention, contributing to health surveillance and emergency management with innovative solutions.

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Medical Entomology

The Medical Entomology Unit focuses on haematophagous diptera, which act as vectors of arboviral diseases in animals and humans. In particular, it carries out diagnostic, surveillance, research, and cooperation activities related to Culicidae (mosquitoes), Culicoides, and the viral diseases they transmit.

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Sample Reception and Quality Control

The Sample Reception and Quality Control Unit manages relationships with clients and the public, ensuring the provision of the Institute's diagnostic services in compliance with quality standards. The Unit is responsible for verifying incoming samples for analytical activities, recording them, forwarding them to the designated laboratories, and preparing test reports with the analytical results obtained.

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Contaminants and Pesticide Residues

The unit conducts analyses of pesticide residues, inorganic contaminants, and trace elements in food and feed, along with the detection of process contaminants and persistent organic pollutants (POPs). It also operates as the National Reference Laboratory (NRL) for Halogenated Persistent Organic Pollutants in food for human and animal consumption, carrying out specialised monitoring and analysis in this critical area.

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Bacteriology and Bacterial Antigen Development

The Unit focuses on the research and diagnosis of bacterial pathogens, with particular attention to foodborne pathogens and the analysis of antimicrobial resistance (AMR). Its diagnostic services include advanced bacterial identification (MALDI-TOF, PCR, WGS), antibiotic susceptibility testing, monitoring of veterinary drugs, and molecular diagnostics. The laboratory also participates in innovative national and international research projects on zoonoses, bacterial vaccine development, and AMR surveillance, aiming to contribute to improvements in global public and veterinary health.

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Animal Breeding and Experimental Studies

The Animal Breeding and Experimental Research Unit provides technical support for activities related to basic and applied scientific research, implementing experimental procedures based on the 3Rs principles: Replacement, Reduction, and Refinement. The Unit collaborates with public and private institutional partners involved in both medical and veterinary research. Animal welfare principles guide all activities within the Unit, which offers its expertise to support research projects and contribute to the activities of the IZS Teramo Centres of Excellence, specifically the EU Reference Centre for the Welfare of Ruminants and Equines and the WOAH Collaborating Centre for Animal Welfare.

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Production of Bacterial Vaccines and Diagnostic Tools

The Unit specialises in the production of bacterial vaccines, diagnostic tools, reagents, and culture media to support the diagnosis and control of infectious animal diseases.

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Diagnostics and Anatomic Pathology

The unit performs microbiological, anatomical-pathological, histological, mycological, and parasitological analyses to identify the aetiological causes of diseases in domestic animals and wildlife, providing expert opinions and interpretations based on laboratory results. It conducts research in the field of comparative oncology and on certain bacterial and parasitic agents responsible for zoonoses. It also manages and updates the Animal Tumour Registry of the Abruzzo Region.

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Epidemiology, Risk Analysis and Information

A team of epidemiologists supporting the relevant offices of the Directorates-General of the Ministry of Health, regional authorities, and local health services in epidemiological analysis and risk assessment related to animal diseases, zoonoses, and food contamination (both biological and chemical). The team is also committed to developing, promoting, and disseminating new approaches and methodologies for risk assessment in the field of veterinary public health.

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Food Hygiene and Technology

The unit conducts analytical investigations on food for human and animal consumption, performing tests to identify and quantify pathogenic microorganisms and hygiene indicators in food production processes. It also carries out analyses for the detection of Genetically Modified Organisms (GMOs). The unit handles the genotypic characterization of foodborne pathogens to support epidemiological investigations and trace the sources of foodborne infections. It provides scientific consultancy and training for official laboratories and competent authorities, while collaborating in its areas of scientific expertise.

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Aquatic Biology

Research and experimentation activities on aquatic ecosystems to promote environmental protection, animal health, and public health within a One Health framework. Conducting ecotoxicological tests in aquatic ecosystems. The Laboratory serves as the Reference Laboratory for the Abruzzo Region in the field of professional and recreational fishing and aquaculture, as established by Regional Law No. 28 of 27 April 2017 concerning the management of fish fauna and the regulation of fishing in inland waters.

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Exotic Disease Diagnostics and Surveillance

As an integral part of CESME, the unit primarily focuses on the diagnosis of viral infectious diseases that are absent or sporadically present in Italy. Its activities also include the monitoring and control of the viruses responsible for these diseases, which pose a potential risk to public health. The unit ensures early diagnoses to enable timely interventions and promotes surveillance plans to address health emergencies and protect the population, while also fostering collaboration between institutions and communities.

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Immunology and Serology

The unit specialises in the serological diagnosis of infectious animal diseases of viral, bacterial, and parasitic origin. It supports health surveillance for various diseases affecting livestock and companion animals, some of which are transmissible to humans. Research activities include advanced studies in applied immunology and proteomics for a detailed characterisation of host–pathogen interactions and the development of diagnostic methods or vaccine-based tools. These studies contribute to diagnostic innovation and to a better understanding of the immunopathogenetic mechanisms of infectious diseases, improving strategies for prevention and health control.

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Animal Welfare

The primary objective of the Unit is to enhance activities in the field of animal welfare, a key element for ensuring the sustainability of livestock production and improving the management of stray animals. Additionally, the Unit aims to embed environmental sustainability and circular economy principles into its core activities, with the ambition of establishing the Institute as a reference point in these priority areas.

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Production of Viral Vaccines and Diagnostic Tools

The Unit's objectives include the development of safe and effective vaccines to counter emerging exotic diseases, as well as the study, validation, and production of diagnostic tools to monitor the spread of endemic and exotic diseases present in, or at risk of being introduced into, our country. These goals align with the EU Animal Health Strategy and the One Health principle, as outlined in Regulation (EU) 2016/429.

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Computational Biology and Bioinformatics

The Unit develops bioinformatics tools for pathogen characterisation and advanced machine learning models to predict pathogen phenotypes from genomic data. These resources are made available through the national bioinformatics platform of the National Reference Centre GENPAT, a key tool for genomic surveillance of pathogenic microorganisms within a One Health framework.
The Unit primarily develops open-source software components, which are shared with the scientific community.

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Aquatic and Terrestrial Ecosystems

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Molecular Biology and Omic Technologies

The Unit is responsible for sequencing and genomic analysis of microorganisms, conducting 16S rRNA and shotgun metagenomics studies from biological samples, as well as transcriptomics research. It develops and validates protocols for bacterial and viral genome sequencing and performs genotype analysis of the prion protein (PrP) in sheep. The Unit works in collaboration with the Bioinformatics Unit to update the CRN platform for the genomic sequences of pathogenic microorganisms, contributing to the database and supporting the development of new bioinformatics tools for pathogen surveillance.

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International Relations and Training

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Epidemiology

A multidisciplinary team of researchers engaged in the study of animal disease epidemiology, zoonotic diseases (those transmitted from animals to humans), and food contamination, with a focus on evaluating the associated risks to animal and human health. Through advanced techniques in data analysis, modelling, and the development of analytical procedures, the laboratory supports health authorities by providing essential information for selecting the most appropriate strategies for prevention and control.

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Animal Health

The laboratory coordinates the specialised units for the diagnosis and control of animal diseases and zoonoses, ensuring compliance with appropriate operational standards. It works closely with regional and national authorities to manage key prophylaxis plans, maintaining ongoing communication with local stakeholders to ensure effective interventions. Additionally, it provides specialist guidance for research activities, aligning its work with the Institute’s strategic objectives.

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Microbiological Food Safety

The Laboratory provides technical and scientific support to official control authorities, agri-food companies, and consumers to ensure the safety of food intended for both humans and animals.

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Production of Diagnostic, Reagents and Vaccines

The Laboratory is responsible for producing vaccines, diagnostic tools, and therapeutic agents aimed at preventing, diagnosing, and treating contagious and zoonotic animal diseases, both in livestock and companion animals. Over the years, production has expanded and diversified to meet the evolving needs of its clients.

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Development and Territory

The Laboratory promotes and supports research activities aimed at the molecular characterization of complex biological systems, applying a holistic approach to develop innovative diagnostic pathways. These activities are carried out in collaboration with other IZSAM laboratories and national and international research institutions.

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+ - Reference centres

National Reference Centre for Brucellosis

By Ministerial Decree of 4 October 1999, published in the Official Gazette of the Italian Republic (G.U.R.I.)...

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Veterinary Epidemiological Observatory of the Abruzzi region (OEVRA)

By Regional President’s Decree No. 43/2015 of 2 April 2015, the Veterinary Epidemiological Observatory...

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CEA - Environmental Education Centre

Regional Law No. 122 of 29 November 1999 outlines the measures concerning Environmental Education in...

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Marine Ecosystems and Fisheries Research Centre

The Marine Ecosystems and Fisheries Research Centre operates in the fields of food hygiene and the health...

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Regional Reference Laboratory for Pathogenic Enterobacteria

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European Union Reference Laboratory (EURL) for Rift Valley fever

The European Union Reference Laboratory (EU-RL) for Rift Valley Fever (RVF) ensures high-quality diagnostic...

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National Reference Centre for Urban Hygiene and Non-Epidemic Emergencies (IUVENE)

The National Reference Centre IUVENE supports the Ministry of Health in managing stray animal populations,...

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European Union Reference Centre for Animal Welfare Ruminants and Equines

The Istituto Zooprofilattico of Abruzzo and Molise has been designated as the EU Reference Centre for...

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FAO Reference Centre for One Health

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FAO Reference Centre for Animal Health and Food Safety

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FAO Reference Centre for Zoonotic Coronaviruses

Since June 2022, the Istituti Zooprofilattici Sperimentali of the Venezie and of Abruzzo and Molise have...

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FAO Reference Centre for Veterinary Epidemiology

The FAO Reference Centre for Veterinary Epidemiology provides expertise in risk assessment, disease surveillance,...

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WOAH Reference Laboratory for West Nile Fever

The WOAH Reference Laboratory for West Nile Fever develops, standardises, and validates diagnostic methods,...

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WOAH Reference Laboratory for Bluetongue

The WOAH Reference Laboratory for Bluetongue carries out diagnostic, scientific training, and research...

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WOAH Reference Laboratory for Contagious Bovine Pleuropneumonia (CBPP)

The Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise was designated as a WOAH Reference...

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WOAH Reference Laboratory for Brucellosis

The WOAH Reference Laboratory for Brucellosis supports surveillance, control, and diagnosis at an international...

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WOAH Collaborating Centre for Veterinary Training and Capacity Building

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WOAH Collaborating Centre for Epidemiology, Modelling and Surveillance

The WOAH Collaborating Centre for Epidemiology, Modelling and Surveillance provides technical and scientific...

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WOAH Collaborating Centre for Animal Welfare

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WOAH Collaborating Centre for Animal Production Food Safety

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National Reference Laboratory for Peste des petits ruminants

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National Reference Laboratory for Capripox Viruses

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National Reference Laboratory for African Horse Sickness

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National Reference Laboratory for Bluetongue

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National Reference Laboratory for Brucellosis

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National Reference Laboratory for Persistent Halogenated Organic Pollutants in Feed and Food

The monitoring and detection of halogenated persistent organic pollutants, chemical compounds known for...

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National Reference Laboratory for Campylobacter

The National Reference Laboratory for Campylobacter serves as a technical and scientific hub that ensures...

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National Reference Laboratory for Listeria monocytogenes

The National Reference Laboratory for Listeria monocytogenes is responsible for collaborating with the...

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National Service Centre for Animal Identification and Registration Database (CSN)

The National Services Centre (Centro Servizi Nazionale – CSN) was established at the Istituto Zooprofilattico...

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National Reference Centre for Foreign Animal Diseases (CESME)

The National Reference Centre supports the management and governance activities of the National Health...

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National Reference Centre for Veterinary Epidemiology, Programming, Information and Risk Analysis (COVEPI)

The National Reference Centre for Veterinary Epidemiology, Programming, Information and Risk Analysis...

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National Reference Center for Whole Genome Sequencing of microbial pathogens: database and bioinformatic analysis (GENPAT)

By Ministerial Decree of 30 May 2017, the Ministry of Health established the National Reference Center...

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