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I principali avvenimenti di interesse epidemiologico in Unione Europea ed in altri Paesi a noi vicini


 

The One Health Concept : the same concept of “Teamworking”

 

Although the term "One Health" (OH) is fairly new, the concept has long been recognized both nationally and globally. Since the XVIII th century, scientists have noted the similarity in disease processes among animals and humans, but human and animal medicines were practiced separately until the 20th century. An example of this insight, in this regard, is the literarycornerstone - “De bovilla peste” - published in 1715 by Giovanni Maria Lancisi can be considered the most relevant proof of a joint management both from human and veterinary side as a unique medicine in the European history of animal diseases. Giovanni Maria Lancisi was a physician, archiater of the pope, well-known as an anatomist and epidemiologist who made an important contribution to veterinary medicine of when rinderpest (cattle plague) affected Europe in the XVIIIth century. His book illustrates the characteristics of cattle plague and, above all, the control measures were discussed. Of the control measures, the most relevant were the introduction of stamping out, with special instructions for the killing and burial of affected animals, the prohibition of animal movements, the adoption of special hygienic and political measures. The relationships between cattle plague and poverty and famine are described, together with the actions taken to deal with them. Lancisi pointed out the relationship between politics and history on the one hand and cattle plague on the other.

In recent years, through the support of key individuals and vital events, the OH concept has gained more recognition in the public health and animal health communities. The OH concept recognizes that the health of humans is interconnected with that of animals and both sharing the same environment. In the history of OH concept different people and a lot of events took turns :

 

  • 1821-1902:
    Virchow recognizes the link between human and animal health. He coined the term "zoonosis" to indicate an infectious disease that is passed between humans and animals.

 

  • 1849-1919:
    William Osler, father of veterinary pathology.

 

  • 1947:
    The Veterinary Public Health Division is established at CDC. With this Division at CDC, the principles of veterinary public health were introduced to the United States and other countries around the world.

 

  • 1927-2006:
    Calvin Schwabe coins the term "One Medicine" and calls for a unified approach against zoonoses that uses both human and veterinary medicine.

 

  • 2004:
    The Wildlife Conservation Society publishes the 12 Manhattan Principles. 12 priorities to combat health threats to human and animal health.

 

  • 2007:
    - The American Medical Association passes the One Health resolution promoting partnership between human and veterinary medicine.
    - The One Health approach is recommended for pandemic preparedness. The representatives of 111 countries and 29 international organizations met in New Delhi India for the International Ministerial Conference on Avian and Pandemic Influenza.

 

  • 2008:
    - FAO, OIE, and WHO collaborate with UNICEF, UNSIC, and the World Bank to develop a joint strategic framework in response to the evolving risk of emerging and re-emerging infectious diseases
    - One Health becomes a recommended approach and a political reality.

 

  • 2009: The One Health Office is established at CDC.
    - The United States Agency for International Development (USAID) establishes the Emerging Pandemic Threats program.
    - Key recommendations for One World, One Health™ are developed.

 

  • 2010:
    - The Hanoi Declaration, which recommends broad implementation of One Health, is adopted unanimously. A total of 71 countries and regional bodies, along with representatives from international organizations, development banks and other stakeholders, attended the International Ministerial Conference on Avian and Pandemic Influenza in Hanoi, Vietnam.
    - The Tripartite Concept Note is published. the Food and Agriculture Organization of the United Nations (FAO), the World Organisation for Animal Health (OIE), and the World Health Organization (WHO) joined together to publish the Tripartite Concept Note.
    - Experts identify clear and concrete actions to move the concept of One Health from vision to implementation.
    - The United Nations and the World Bank recommend adoption of One Health approaches.
    - The European Union reaffirms its commitment to operate under a One Health umbrella.

 

  • 2011:
    - The 1st International One Health Congress is held in Melbourne, Australia.
    - The 1st One Health Conference in Africa is held.
    - The High Level Technical Meeting to Address Health Risks at the Human-Animal-Ecosystem Interface builds political will for the One Health movement.

 

  • 2012:
    - The Global Risk Forum sponsors the first One Health Summit.

 

  • 2013:
    - The 2nd International One Health Congress is held in conjunction with the Prince Mahidol Award Conference.

 

OH is not a new concept, but it has become more important in recent years because many factors have changed the interactions among humans, animals, and the environment. These changes have caused the emergence and re-emergence of many diseases. Nowadays, humankind faces many challenges requiring global responses and solutions. One of these challenges is the spread of emerging infectious diseases (EIDs) from the interfaces between animals and humans and the ecosystems in which they live. EIDs may be defined as infections that have newly occurred in a population or have existed previously but are rapidly increasing in incidence or geographic range. The emergence and spread of EIDs are the result of several phenomena, including the exponential growth in human and livestock populations, rapid urbanization, changing in farming systems and husbandry, closer contacts between livestock and wildlife, forest encroachment, changes in ecosystems and globalization of animal and animal products trade (Table 1).

 
 

Table 1. Mainly causes and related effects influencing the emergence and reemergence of many diseases

Table 1
 
 

Animal disease is a critical driver of poverty and a source of significant human morbidity and mortality, and thus deserves the re-invigorated focus brought by OH. In the face of a human population of nine billion in the next half century, finding ways to produce safe, secure and sustainable food through improved livestock systems will become an increasingly important role for OH. The recent shift in OH investment and effort towards endemic zoonoses, livestock diseases and food safety is a necessary development to ensure this approach remains relevant beyond the spectrum of emerging infections.

 

Successful public health interventions require the cooperation of the human health, veterinary health, and environmental health communities. According Center for Disease Control and Prevention (CDC), about 75 % of recently emerging infectious diseases affecting humans are of animal origin, and about 60 % of all human pathogens are zoonotic. What many do not realize is that these diseases do not just wreak havoc on human health. They leave collateral damage along the way, killing livestock, reducing the number of qualified health workers and educators, creating political unrest, and stopping the progress of developing nations. Most of the fundamental social and environmental determinants of health, such as water security, biodiversity, climate change, social justice, equitable access to resources, pollution and land use planning, have remained beyond the scope of most OH programmes, despite their profound impacts on human and animal health and welfare. Two factors that could be driving the more specific focus on infectious diseases in One Health are:

 

i ) the desire to reduce economic losses and to ensure access to markets by meeting the legislated obligations to attest to freedom from specific infectious diseases of animals, and

ii) the investment of resources from the public health sector for emerging zoonotic disease research and control programs. For years OH has focused its efforts on controlling disease rather than on protecting and promoting health. Health is more than the absence of disease. Health is a reflection of how individuals or populations interact with their world to cope and recover from stressors or changes, often what ecologists refer to as ‘resilience’ defined as the capacity of an ecosystem to respond to a perturbation or disturbance by resisting damage and recovering quickly.

 

Although the concept of One Health was not new—the theory was supported by William Osler and Rudolf Virchow, the Father of Comparative Pathology, and re-articulated in Calvin Schwabe’s Veterinary Medicine and Human Health in 1984—our increasing interdependence with animals and their products has spurred the human medical and veterinary professions to readdress such an approach. This approach would encourage the collaborative efforts of multiple disciplines working locally, nationally and globally to attain the best possible health for people, animals and environment.

 

The benefits of a One Health approach include:

 

1. Improving animal and human health globally through collaboration among all the health sciences, especially between the veterinary and human medical professions, to address critical needs,

2. Meeting new global challenges head-on through collaboration among multiple professions—veterinary medicine, human medicine, environmental conditions, wildlife health and public health,

3. Developing centres of excellence for education and training in specific areas through enhanced collaboration among colleges and schools of veterinary medicine, human medicine and public health,

4. Increasing professional opportunities for veterinarians,

5. Adding to our scientific knowledge to create innovative programmes to improve health.

 

Actions against diseases at the animal–human–ecosystems interface must be based on prevention. The prevention of crossing ecosystem boundaries by diseases requires the existence of effective surveillance systems, focusing all relevant ecosystems involved or potentially involved and an appropriate multidisciplinary and inter-sectorial cooperation. During the surveillance of the animal–human–ecosystems interface, and when actions to prevent the crossing of ecosystem boundaries must be defined, no single method is valid for all diseases and situations. The approaches to be used are indeed rather intrinsic to the specific environment and disease we are facing and should be defined following an accurate retrospective and holistic analysis of the epidemiology of the disease under consideration, the environmental situation, the production systems involved (considered from farm to fork in case of food-borne diseases) and the historical information available. Finally, a proper integration of local needs with the requirements for international surveillance of EIDs is essential for a fair relationship between countries assuring local authorities active cooperation.

 

Recognizing that human health, animal health, and ecosystem health are inextricably linked, OH seeks to promote, improve, and defend the health and well-being of all species by enhancing cooperation and collaboration between physicians, veterinarians, other scientific health and environmental professionals and by promoting strengths in leadership and management to achieve these goals.

 

In conclusion we can statethat OH approach shall be achieved through:

1. Joint educational efforts between human medical, veterinary medical schools, and schools of public health and the environment;
2. Joint communication efforts in journals, at conferences, and via allied health networks;
3. Joint efforts in clinical care through the assessment, treatment and prevention of cross-species disease transmission;
4. Joint cross-species disease surveillance and control efforts in public health;
5. Joint efforts in better understanding of cross-species disease transmission through comparative medicine and environmental research;
6. Joint efforts in the development and evaluation of new diagnostic methods, medicines and vaccines for the prevention and control of diseases across species and;
7. Joint efforts to inform and educate political leaders and the public sector through accurate media publications.

 
 

References



  1. Calistri P., Iannetti S., Danzetta M. L., Narcisi V., Cito F., Di Sabatino D., Bruno R., Sauro F., Atzeni M., Carvelli A. and Giovannini A., 2012. The Components of ‘One World – One Health’ Approach. Transboundary and Emerging Diseases. 60 (Suppl. 2) 4–13
  2. Gunnarsson S. (2006). The conceptualization of health and disease in veterinary medicine. Acta vet. scand.,48 (1), 20.
  3. King, L.-J., 2008: Executive summary of the AVMA one health initiative task force report. JAVMA 233, 259–261.
  4. Mantovani A, Zanetti R., 1993. Giovanni Maria Lancisi: De bovilla peste and stamping out. Hist Med Vet. 1993;18(4):97-110.
  5. Morens, D.-M., G. K. Folkers, and A. S. Fauci, 2004: The challenge of emerging and re-emerging infectious diseases. Nature 430, 242–249.
  6. Morse, S.-S., 2004: Factors and determinants of disease emergence. Rev. Sci. Tech. 23, 443–451.
  7. Stephen C. & Karesh W .B., 2014. Is One Health delivering results? Rev. sci. tech. Off. int. Epiz., 2014,33 (2), 375-379.
 
 

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