e-ISSN 1828-1427
Rivista trimestrale di Sanità Pubblica Veterinaria edita dall'Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise ‘G. Caporale’
A quarterly journal devoted to veterinary public health, veterinary science and medicine published by the Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise ‘G. Caporale’ in Teramo, Italy
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ISSUES ONLINE
| 2014 - Volume 50 (4), October-December | |||
| Aurelio Muttini, Michele Abate, Nicola Bernabò, Francesco Cavani, Rossella Mingozzi, Umberto Tosi, Matteo Cadossi, Stefania Setti, Sandro Giannini, Rocco Leone & Luca Valbonetti | |||
| Effect of electric current stimulation in combination with external fixator on bone healing in a sheep fracture model | 249-257 | ||
| doi: 10.12834/VetIt.271.963.2 |
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Summary Biophysical stimulations with electric and electromagnetic fields have been demonstrated to accelerate the bone-healing rate. This study has been designed to investigate the effects of electricity directly connected with the central pins of an external fixator in an experimental osteotomy model in sheep. Thirty mg/kg of tetracycline chloride were administered on the 30th and on the 45th day after surgery for histomorphometric studies. Plain radiographs were obtained in standard projections every 15 days after surgery and were analyzed with a software program (Corel Photo-Paint Pro X2, Corel Corporation, Ottawa, Canada). The specimens obtained after 60 days were examined with histological analysis. The results show that biophysical treatment with alternating electricity in combination with external fixator enhances new-bone formation. The translational value of this study, due to the similarities between ovine and human species, suggests that this treatment could be useful in speeding the bone-healing rate both in animals and humans. Keywords |
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