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e-ISSN 1828-1427

 

Rivista trimestrale di Sanità Pubblica Veterinaria edita dall'Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise ‘G. Caporale’

A quarterly journal devoted to veterinary public health, veterinary science and medicine published by the Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise ‘G. Caporale’ in Teramo, Italy


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2014 - Volume 50 (1), January-March
   
 
Maria Teresa Antognoni, Fabrizia Veronesi, Giulia Morganti, Vittorio Mangili, Gabriele Fruganti & Arianna Miglio  
Natural infection of Anaplasma platys in dogs from Umbria region (Central Italy) 49-56
doi: 10.12834/VetIt.82.258.2
 
Summary
Anaplasma platys is a tick-borne pathogen causing the Infectious Canine Cyclic Thrombocytopenia. The pathogenesis of this disease is not yet well understood, due to the wide variety of clinico-pathological patterns described worldwide and to the high prevalence of co-infections with other vector-borne pathogens occurring in endemic areas. The present paper reports 3 cases of infection by A. platys occurring in dogs native to Central Italy, considered a non-endemic area to date. Infections were initially diagnosed based on clinical data and observation of morulae within platelets and then confirmed by biomolecular techniques. Moreover, two dogs showed an immune-mediated hemolytic anemia, as yet not described in literature in association with A. platys infection. The symptoms and the pathological findings observed will be discussed, as well as the importance to include this pathogen in the differential diagnosis of tick-borne diseases even in Central Italy.

Keywords
Anaplasma platys, Central Italy, Diagnosis, Dog, Immune-Mediated Hemolytic Anemia, Thrombocytopenia.


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