The central headquarters of the Istituto G. Caporale is at Teramo (Abruzzo), on the edge of the historic centre of the city.

There are also five area diagnostic centres in Abruzzo and Molise, located at Avezzano (Province of L'Aquila, Abruzzo), Pescara (Abruzzo), Lanciano (Province of Chieti, Abruzzo), Campobasso (Molise) and Isernia (Molise).

At Termoli (Province of Campobasso, Molise) there is the Regional Centre for Fishing and Aquaculture, while the Cerrano Tower at Pineto (Province of Teramo, Abruzzo) houses the International Centre for Veterinary Training and Information.